87. Kocsis GF, Pipis J, Fekete V, Kovacs-Simon A, Odendaal L, Molnar E, Giricz Z, Janaky T, van Rooyen J, Csont T, Ferdinandy P.
Lovastatin interferes with the infarct size-limiting effect of ischemic preconditioning and postconditioning in rat hearts.
Am J Physiol Heart Circ Physiol. 2008 May;294(5):H2406-H2409. Download Pdf

86. Faragó N, Kocsis GF, Fehér LZ, Csont T, Hackler L Jr, Varga-Orvos Z, Csonka C, Kelemen JZ, Ferdinandy P, Puskás LG.
Gene and protein expression changes in response to normoxic perfusion in mouse
hearts.
J Pharmacol Toxicol Methods. 2008 Mar-Apr;57(2):145-54.

85. Dormán G, Kocsis-Szommer K, Spadoni C, Ferdinandy P.
MMP inhibitors in cardiac diseases: an update.
Recent Patents Cardiovasc Drug Discov. 2007 Nov;2(3):186-94. Review.

84. Ferdinandy P, Schulz R, Baxter GF.
Interaction of cardiovascular risk factors with myocardial ischemia/reperfusion injury, preconditioning, and postconditioning.
Pharmacol Rev. 2007 Dec;59(4):418-58. Review.

83. Bencsik P, Kupai K, Giricz Z, Görbe A, Huliák I, Fürst S, Dux L, Csont T,Jancsó G, Ferdinandy P.
Cardiac capsaicin-sensitive sensory nerves regulate myocardial relaxation via S-nitrosylation of SERCA: role of peroxynitrite.
Br J Pharmacol. 2008 Feb;153(3):488-96.

82. Stef G, Csiszar A, Ziangmin Z, Ferdinandy P, Ungvari Z, Veress G.
Inhibition of NAD(P)H oxidase attenuates aggregation of platelets from high-risk cardiac patients with aspirin resistance.
Pharmacol Rep. 2007 Jul-Aug;59(4):428-36.

81. Burley DS, Ferdinandy P, Baxter GF.
Cyclic GMP and protein kinase-G in myocardial ischaemia-reperfusion: opportunities and obstacles for survival signaling.
Br J Pharmacol. 2007 Nov;152(6):855-69. Review.

80. Csont T, Bereczki E, Bencsik P, Fodor G, Görbe A, Zvara A, Csonka C, Puskás LG, Sántha M, Ferdinandy P.
Hypercholesterolemia increases myocardial oxidative and nitrosative stress thereby leading to cardiac dysfunction in apoB-100 transgenic mice.
Cardiovasc Res. 2007 Oct 1;76(1):100-9.

79. Bereczki E, Gonda S, Csont T, Korpos E, Zvara A, Ferdinandy P, Santha M.   
Overexpression of biglycan in the heart of transgenic mice: an antibody microarray study.
J Proteome Res. 2007 Feb;6(2):854-61.

78. Orosz Z, Csiszar A, Labinskyy N, Smith K, Kaminski PM, Ferdinandy P, Wolin MS, Rivera A, Ungvari Z.
Cigarette smoke-induced proinflammatory alterations in the endothelial phenotype: role of NAD(P)H oxidase activation.
Am J Physiol Heart Circ Physiol  292:H130-139 (2007)

77. Balogh E, Czuriga I, Bereczky Z, Boda K, Koszegi Z, Konya C, Csaszar A, Muszbek L, Edes I, Ferdinandy P.  
[Increase of homocysteine in cardiovascular diseases in Hungary]
Orv Hetil 147:1685-1690 (2006) [In Hungarian].

76. Gyongyosi M, Strehblow C, Sperker W, Hevesi A, Garamvolgyi R, Petrasi Z, Pavo N, Ferdinandy P, Csonka C, Csont T, Sylven C, Declerck PJ, Pavo I Jr, Wojta J, Glogar D, Huber K. 
Platelet activation and high tissue factor level predict acute stent thrombosis in pig coronary arteries: prothrombogenic response of drug-eluting or bare stent implantation within the first 24 hours.
Thromb Haemost 96:202-209 (2006)

75. Bjelik A, Bereczki E, Gonda S, Juhasz A, Rimanoczy A, Zana M, Csont T, Pakaski M, Boda K, Ferdinandy P, Dux L, Janka Z, Santha M, Kalman J.   
Human apoB overexpression and a high-cholesterol diet differently modify the brain APP metabolism in the transgenic mouse model of atherosclerosis.
Neurochem Int 49:393-400 (2006)

74. Ferdinandy P.   
Peroxynitrite: just an oxidative/nitrosative stressor or a physiological regulator as well?
Br J Pharmacol 148:1-3 (2006) [review]

73. Turan N, Csonka C, Csont T, Giricz Z, Fodor G, Bencsik P, Gyongyosi M, Cakici I, Ferdinandy P.
The role of peroxynitrite in chemical preconditioning with 3-nitropropionic acid in rat hearts.
Cardiovasc Res  70:384-390 (2006) 

72. Kónya C, Ferdinandy P.
Vitamin C: new role of the old vitamin in the cardiovascular system?
Br J Pharmacol 147:125-127 (2006) [review]

71. Giricz Z, Lalu MM, Csonka C, Bencsik P, Schulz R, Ferdinandy P.
Hyperlipidemia attenuates the infarct-size limiting effect of ischemic preconditioning: role of matrix metalloproteinase-2 inhibition.
J Pharmacol Exp Ther  316:154-61 (2006) [Epub 2005 Sep 15]

70. Sőti C,  Nagy E,  Giricz Z, Vígh L, Csermely P, Ferdinandy P.
Heat shock proteins as emerging therapeutic targets.
Br J Pharmacol  146:769-80 (2005) [review]

69. Zvara A, Bencsik P, Fodor G, Csont T, Hackler Jr L, Dux M, Fürst S, Jancsó G, Puskás LG, Ferdinandy P. Capsaicin-sensitive sensory neurons regulate myocardial function and gene expression pattern of rat hearts: a DNA microarray study.
FASEB J 20:160-162 (2006) [Epub 2005 Nov 8]

68. Ungi I, Ungi T, Ruzsa Z, Nagy E, Zimmermann Z, Csont T, Ferdinandy P.
Hypercholesterolemia attenuates the anti-ischemic effect of preconditioning during coronary angioplasty.
Chest 128:1623-1628 (2005)

67. Csont T, Ferdinandy P.
Direct myocardial protective effect of glyceryl trinitrate: beyond vascular nitrate tolerance.
Pharmacol Therapeut 105:57-68 (2005) [review]

66. Puskas LG, Bereczki E, Santha M, Vigh L, Csanadi G, Spener F, Ferdinandy P, Onody A, Kitajka K.
Cholesterol and cholesterol plus DHA diet-induced gene expression and fatty acid changes in mouse eye and brain.
Biochimie 86:817-24 (2004)

65. Katona M, Boros M, Santha P, Ferdinandy P, Jancso G.
Selective sensory denervation by capsaicin aggravates adriamycin-induced cardiomyopathy in rats.
Naunyn-Schmiedeberg's Arch Pharmacol  370:436-443 (2004)

64. Puskás LG, Nagy ZB, Giricz Z, Ónody A, Csonka C, Kitajka K, Hackler Jr L, Zvara A, Ferdinandy P.
Cholesterol diet-induced hyperlipidemia influences gene expression pattern of rat hearts: a DNA microarray study.
FEBS Lett  562:99-104 (2004)

63. Csont T, Csonka C, Kovacs P, Jancso G, Ferdinandy P.
Capsaicin-sensitive sensory neurons regulate myocardial nitric oxide and cGMP signaling.
Eur J Phramacol 476:107-13 (2003)

62. Giricz Z, Csonka C, Ónody A, Csont T, Ferdinandy P.
Role of cholesterol-enriched diet and the mevalonate pathway in cardiac nitric oxide synthesis.
Basic Res Cardiol 98:304-10 (2003)
   
61. Radak Z, Ogonovszky H, Dubecz J, Pavlik G, Sasvari M, Pucsok J, Berkes I, Csont T, Ferdinandy P.
Super-marathon race increases serum and urinary nitrotyrosine and carbonyl levels.
Eur J Clin Invest 33:726-30 (2003)

60. Csonka C, Ónody A, Csont T, Ferdinandy P.
The defibrillatory action of glibenclamide is independent from ATP-sensitive K+-chanels and free radicals.
J Cardiovasc Pharmacol 41:916-922 (2003)

59. Ónody A, Csonka C, Giricz Z, Ferdinandy P.
Hyperlipidemia induced by cholesterol-rich diet leads to enhanced peroxynitrite formation in rat hearts.
Cardiovasc Res 58:663-670 (2003)

58. D'Souza SP, Yellon DM, Martin C, Schulz R, Heusch G, Onody A,  Ferdinandy P, Baxter GF.
Type-B natriuretic peptide (BNP) limits infarct size in rat isolated heart via KATP channel opening.
Am J Physiol Heart Circ Physiol 284:H1592-600 (2003)

57. Ónody A, Zvara A, Hackler L Jr., Vígh L, Ferdinandy P, Puskás LG.
Effect of classic preconditioning on the gene expression pattern of rat hearts: a DNA microarray study.
FEBS Lett 536: 35-40 (2003)

56. Gao C, Sawicki G,  Suarez-Pinzon WL, Csont T, Wozniak M, Ferdinandy P, Schulz R.
Matrix metalloproteinase-2 mediates cytokine-induced myocardial contractile dysfunction.
Cardiovasc Res 57:426-33 (2003)

55. Ferdinandy P, Schulz R.
Nitric oxide, superoxide, and peroxynitrite in myocardial ischemia-reperfusion injury and preconditioning.
Br J Pharmacol 138: 532-543 (2003) [review]

54. Ferdinandy P.
Myocardial ischemia/reperfusion injury and preconditioning: effects of hypercholesterolemia/hyperlipidemia.
Br J Pharmacol 138: 283-285 (2003) [review]

53. Gyongyosi M, Sperker W, Csonka Cs, Bonderman D, Lang I, Strehblow C, Adalbrecht C, Shirazi M, Windberger U, Marlovits S, Gottsauner-Wolff M, Wexberg P, Kockx M, Ferdinandy P, Glogar D.
Inhibition of interleukin-1beta convertase is associated with decrease of neointimal hyperplasia after coronary artery stenting in pigs.
Mol Cell Biochem 249:39-43 (2003)

52. Lalu MM, Csonka C, Giricz Z, Csont T, Schulz R, Ferdinandy P.
Preconditioning decreases ischemia/reperfusion-induced release and activation of matrix metalloproteinase-2.
Biochem Biophys Res Commun 296:937, (2002)

51. Khadour FH, Panas D, Ferdinandy P, Schulze C, Csont T, Lalu MM, Wildhirt SM, Schulz R.
Enhanced NO and superoxide generation in dysfunctional hearts from endotoxemic rats.
Am J Physiol Heart Circ Physiol 283:H1108-15, (2002)

50. Csont T, Csonka C, Ónody A, Görbe A, Dux L, Schulz R. Baxter GF, Ferdinandy P.
Nitrate tolerance does not increase production of peroxynitrite in the heart.
Am J Physiol Heart Circ Physiol 283:H69-H76, (2002)

49. Csont T, Balogh G, Csonka C, Boros I, Horvath I, Vigh L, Ferdinandy P.
Hyperlipidemia induced by high cholesterol diet inhibits heat shock response in rat hearts.
Biochem Biophys Res Commun 290:1535-1538 (2002)

48. Sari R, Nemeth J, Porszasz R, Horvath P, Blasig IE, Ferdinandy P, Nagy I, Lonovics J, Szilvassy Z.
Impairment by lovastatin of neural relaxation of the rabbit sphincter of Oddi.
Eur J Pharmacol 432:91-7 (2002)

47. Baxter GF, Ferdinandy P.
Delayed preconditioning of myocardium: current perspectives.
Basic Res Cardiol 96:329-44 (2001) [review]

46. Csonka C, Csont T, Onody A, Ferdinandy P.
Preconditioning decreases ischemia/reperfusion-induced peroxynitrite formation.
Biochem Biophys Res Commun285:1217-9 (2001)

45. Jednakovits A, Ferdinandy P, Jaszlits L, Banyasz T, Magyar J, Szigligeti P, Kortvely A, Szentmiklosi JA, Nanasi PP.
In vivo and in vitro acute cardiovascular effects of bimoclomol.
Gen Pharmacol. 34:363-9 (2000)

44. Pongo E, Balla Z, Mubagwa K, Flameng W, Edes I, Szilvassy Z, Ferdinandy P.
Deterioration of the protein kinase C-K(ATP) channel pathway in regulation of coronary flow in hypercholesterolaemic rabbits.
Eur J Pharmacol 418:217-23 (2001)

43. Pataki T, Bak I, Csonka C, Kovacs P, Varga E, Blasig IE, Tosaki A.
Regulation of ventricular fibrillation by heme oxygenase in ischemic/reperfused hearts.
Antioxid Redox Signal 3:125-34 (2001)

42. Ferdinandy P, Schulz R.
Peroxynitrite: toxic or protective in the heart?
Circ Res 88:E12-E13 (2001) [Letter]

41. Szilvássy Z, Csont T, Droy-Lefaix MT, Ferdinandy P.
Nitric oxide, peroxynitrite, and cGMP in atherosclerosis-induced hypertensive rabbits: beneficial effects of cicletanine.
J Vasc Res 38:39-46 (2001)

40. Ferdinandy P, Schulz R.
Inhibition of peroxynitrite-induced dityrosine formation with oxidized and reduced thiols, NO donors, and purine-derivatives.
Antiox Redox Signal 3:165-171 (2001)

39. Csonka C, Pataki T, Kovacs P, Muller SL, Schroeter ML, Tosaki A, Blasig IE.
Effects of oxidative stress on the expression of antioxidative defense enzymes in spontaneously hypertensive rat hearts.
Free Rad Biol Med 29:612-619 (2000)

38. Ferdinandy P, Daniel H, Ambrus I, Rothery RA, Schulz R.
Peroxynitrite is a major contributor to cytokine-induced myocardial contractile failure in rat hearts.
Circ Res 87:241-247 (2000)

37. Kovacs P, Szilvassy Z, Hegyi P, Nemeth J, Ferdinandy P, Tosaki A.
Effect of transdermal nitroglycerin on glucose-stimulated insulin release in healthy male volunteers.
Eur J Clin Invest 30:41-44 (2000)

36. Csont T, Szilvássy Z, Fülöp F, Nedeianu S, Páli T, Tosaki A, Dux L, Ferdinandy P.
Direct myocardial anti-ischaemic effect of GTN in both nitrate-tolerant and nontolerant rats: a cGMP-independent activation of KATP.
Br J Pharmacol 128:1427-1434 (1999)

35. Haines DD, Bak I, Ferdinandy P, Mahmoud FF, Al-Harbi SA, Blasig IE, Tosaki A.
Cardioprotective effects of the calcineurin inhibitor FK506 and the PAF receptor antagonist and free radical scavenger, EGb 761, in isolated ischemic/reperfused rat hearts.
J Cardiovasc Pharmacol 35:37-44 (2000)

34. Varga E, Bodi A, Ferdinandy P, Droy-Lefaix MT, Blasig IE, Tosaki A
The protective effect of EGb 761 in isolated ischemic/reperfused rat hearts: a link between cardiac function and nitric oxide production.
J Cardiovasc Pharmacol 34:711-7 (1999)

33. Csonka C, Szilvassy Z, Fulop F, Pali T, Blasig IE, Tosaki A, Schulz R, Ferdinandy P.
Classic preconditioning decreases the harmful accumulation of nitric oxide during ischemia and reperfusion in rat hearts.
Circulation 100:2260-2266 (1999)

32. Csonka C, Varga E, Kovacs P, Ferdinandy P, Blasig IE, Szilvassy Z, Tosaki A
Heme oxygenase and cardiac function in ischemic/reperfused rat hearts.
Free Rad Biol Med 27:119-26 (1999)

31. Ferdinandy P, Panas P, Schulz R.
Peroxynitrite contributes to spontaneous loss of cardiac efficency in isolated working rat hearts.
Am J Physiol 276:H1861-1867 (1999)

30. Oroszi G, Szilvassy Z, Nemeth J, Ferdinandy P, Szolcsanyi J, Tosaki A
Interaction between capsaicin and nitrate tolerance in isolated guinea-pig heart.
Eur J Pharmacol 1999 Mar 5;368(2-3):R1-3

29. Ferdinandy P, Szilvassy Z, Csont T, Koltai M, Droy-lefaix MT.
Cardioprotective effect of enantiomers of cicletanine (BN50417, BN50418) in ischaemic/reperfused isolated working rat hearts: interaction with glibenclamide.
Pharmacol Res 1999 Mar;39(3):225-231

28. Radak Z, Pucsok J, Mecseki S, Csont T, Ferdinandy P.
Muscle soreness-induced reduction in force generation is accompanied by increased nitric oxide content and DNA damage in human skeletal muscle.
Free Rad Biol Med 26:1059-63 (1999)

27. van Beek JH, Csont T, de Kanter FJ, Bussemaker J.
Simple model analysis of 13C NMR spectra to measure oxygen consumption using frozen tissue samples.
Adv Exp Med Biol. 1998;454:475-85.

26. Szilvassy J, Jancso G, Ferdinandy P
Mechanism of vasodilatation by cochlear nerve stimulation. Role of calcitonin gene-related peptide.
Pharmacol Res 1999 Mar;39(3):217-220

25. Csont T, Pali T, Szilvassy Z, Ferdinandy P.
Lack of correlation between myocardial nitric oxide and cyclic guanosine monophosphate content in both nitrate-tolerant and -nontolerant rats.
Biochem Pharmacol 1998 Nov 1;56(9):1139-44

24. Ferdinandy P, Csonka C, Csont T, Szilvassy Z, Dux L.
Rapid pacing-induced preconditioning is recaptured by farnesol treatment in hearts of cholesterol-fed rats: role of polyprenyl derivatives and nitric oxide.
Mol Cell Biochem 1998 Sep;186(1-2):27-34

23. Szilvassy Z, Ferdinandy P, Cluff CW, Elliott GT.
Antiischemic effect of monophosphoryl lipid A in conscious rabbits with hypercholesterolemia and atherosclerosis.
J Cardiovasc Pharmacol 1998 Aug;32(2):206-12

22. Ferdinandy P, Appelbaum Y, Csonka C, Blasig IE, Tosaki A.
Role of nitric oxide and TPEN, a potent metal chelator, in ischaemic and reperfused rat isolated hearts.
Clin Exp Pharmacol Physiol 1998 Jul-Aug;25(7-8):496-502

21. Ferdinandy P, Szilvassy Z, Baxter GF.
Adaptation to myocardial stress in disease states: is preconditioning a healthy heart phenomenon?
Trends Pharmacol Sci 19:223-9 (1998) [review]

20. Ferdinandy P, Fazekas T, Kadar E.
Effect of orotic acidon ischemic/reperfused myocardial function and glycogen content in isolated working rat hearts.
Pharmacol Res 37:111-114 (1998)

19. Ferdinandy P, Szilvassy Z, Horvath LI, Csont T, Csonka C, Nagy E, Szentgyorgyi R, Nagy I, Koltai M, Dux L.
Loss of pacing-induced preconditioning in rat hearts: role of nitric oxide and cholesterol-enriched diet.
J Mol Cell Cardiol 29:3321-33 (1997)

18. Vigh L, Literati PN, Horvath I, Torok Z, Balogh G, Glatz A, Kovacs E, Boros I, Ferdinandy P, Farkas B, Jaszlits L, Jednakovits A, Koranyi L, Maresca B.
Bimoclomol: a nontoxic, hydroxylamine derivative with stress protein-inducing activity and cytoprotective effects.
Nat Med 3:1150-4 (1997)

17. Ferdinandy P, Csont T, Csonka C, Torok M, Dux M, Nemeth J, Horvath LI, Dux L, Szilvassy Z, Jancso G.
Capsaicin-sensitive local sensory innervation is involved in pacing-induced preconditioning in rat hearts: role of nitric oxide and CGRP?
Naunyn Schmiedebergs Arch Pharmacol 1997 Sep;356(3):356-63

16. Szekeres L, Szilvassy Z, Ferdinandy P, Nagy I, Karcsu S, Csati S.
Delayed cardiac protection against harmful consequences of stress can be induced in experimental atherosclerosis in rabbits.
J Mol Cell Cardiol 1997 Jul;29(7):1977-83

15. Szilvassy Z, Ferdinandy P, Nagy I, Jakab I, Koltai M.
The effect of continuous versus intermittent treatment with transdermal nitroglycerin on pacing-induced preconditioning in conscious rabbits.
Br J Pharmacol 1997 Jun;121(3):491-6

14. Szilvassy J, Ferdinandy P, Kiss JG, Jori J, Muller J, Czigner J.
Involvement of glibenclamide-sensitive potassium channels in vasorelaxation by cochlear nerve stimulation.
Eur Arch Otorhinolaryngol Suppl 1997;1:S6-8

13. Ferdinandy P, Szilvassy Z, Balogh N, Csonka C, Csont T, Koltai M, Dux L
Nitric oxide is involved in active preconditioning in isolated working rat hearts.
Ann N Y Acad Sci 1996 Sep 30;793:489-93

12. Szilvassy Z, Ferdinandy P, Szilvassy J, Nagy I, Karcsu S, Lonovics J, Dux L, Koltai M
The loss of pacing-induced preconditioning in atherosclerotic rabbits: role of hypercholesterolaemia.
J Mol Cell Cardiol 1995 Dec;27(12):2559-69

11. Ferdinandy P, Szilvassy Z, Droy-Lefaix MT, Tarrade T, Koltai M
KATP channel modulation in working rat hearts with coronary occlusion: effects of cromakalim, cicletanine, and glibenclamide.
Cardiovasc Res 1995 Nov;30(5):781-7

10. Ferdinandy P, Szilvassy Z, Csont T, Csonka C, Nagy E, Koltai M, Dux L
Nitroglycerin-induced direct protection of the ischaemic myocardium in isolated working hearts of rats with vascular tolerance to nitroglycerin.
Br J Pharmacol 1995 Aug;115(7):1129-31

9. Ferdinandy P, Szilvassy Z, Koltai M, Dux L
Ventricular overdrive pacing-induced preconditioning and no-flow ischemia-induced preconditioning in isolated working rat hearts.
J Cardiovasc Pharmacol 1995 Jan;25(1):97-104

8. Szilvassy Z, Ferdinandy P, Bor P, Jakab I, Szilvassy J, Nagy I, Lonovics J, Koltai M
Loss of preconditioning in rabbits with vascular tolerance to nitroglycerin.
Br J Pharmacol 1994 Aug;112(4):999-1001

7. Szilvassy Z, Ferdinandy P, Bor P, Jakab I, Lonovics J, Koltai M
Ventricular overdrive pacing-induced anti-ischemic effect: a conscious rabbit model of preconditioning.
Am J Physiol 1994 May;266(5 Pt 2):H2033-41

6. Szilvassy Z, Koltai M, Ferdinandy P, Jakab I, Lonovics J, Tarrade T, Allard M, Braquet PG
Cromakalim and cicletanine against pacing-induced myocardial ischemia in conscious rabbits.
Life Sci 1994;54(9):PL125-30

5. Ferdinandy P, Szilvassy Z, Koltai M, Tarrade T, Allard M, Braquet P.
Cardiac failure in isolated working rat heart: Effect of cicletanine.
Cardiol Elderly 1994 Feb; 2(1):35-44

4. Ferdinandy P, Das DK, Tosaki A
Pacing-induced ventricular fibrillation leading to oxygen free radical formation in aerobically perfused rat hearts.
J Mol Cell Cardiol 1993 Jun;25(6):683-92

3. Szilvassy Z, Jakab I, Ferdinandy P, Koltai M, Lonovics J, Tarrade T, Braquet PG
Zaprinast, cicletanine, and verapamil attenuate overdrive pacing-induced myocardial ischemia in conscious rabbits.
Life Sci 1993;53(1):PL13-8

2. Bouma P, Ferdinandy P, Sipkema P, Allaart CP, Westerhof N
Nitric oxide is an important determinant of coronary flow in the isolated blood perfused rat heart.
Basic Res Cardiol 1992 Nov-Dec;87(6):570-84

1. Ferdinandy P, Koltai M, Tosaki A, Berthet P, Tarrade T, Esanu A, Braquet P
Cicletanine improves myocardial function deteriorated by ischemia/reperfusion in isolated working rat hearts.
J Cardiovasc Pharmacol 1992 Feb;19(2):181-9